Special Section: Tuberculosis
نویسنده
چکیده
Mycobacterium marinum, a close relative of Mycobacterium tuberculosis is being used to study mycobacterial pathogenesis. M. marinum causes a systemic tuberculosis-like infection and disease in ectotherms such as frogs and fish. This review describes the development of M. marinum as a model pathogen and the more recent development of genetically tractable model hosts, namely the zebrafish, Drosophila and Dictyostellium to dissect the complex host-pathogen interactions that lead to tuberculosis.
منابع مشابه
Special Section: Tuberculosis
M. tuberculosis, the causative agent of tuberculosis, has persisted in the human population despite decades of intervention strategies. While our knowledge about the pathogen and the disease process it causes have grown substantially over the years, we are still grappling with devising strategies for its control. This article attempts to understand the infection biology of M. tuberculosis and t...
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تاریخ انتشار 2004